Staff Profiles

Dr Zachariah Matshediso

Dr Matshediso Zachariah

Faculty of Health Sciences

School of Allied Health Professions


Location: Block 246 office A217
Phone: 355-4651

PhD Biochemical Sciences, 2017, University of Surrey,UK

MSc Clinical Biochemistry,2013,University of Surrey, UK

BSc Medical Laboratory Sciences, 2009, University of Botswana

Diploma in Medical Laboratory Technology, 2005 Institute of Health Sciences,Gaborone




I am a Lecturer and Researcher at the  University of Botswana specializing as a Clinical Chemistry Lecturer in the Faculty of Health Sciences. I supervise BSc Medical Laboratory Sciences undergraduate students in their final year research projects and  MPhil/PhD in Medical Sciences students. My research interest is in understanding the role of cellular stress in health and diseases especially non-communicable diseases such as cardiovascular diseases, diabetes mellitus and cancer.


Clinical Chemistry I 

Clinical Chemistry II

MPhil/PhD in Medical Sciences 

Chemical Pathology

Role of ER stress in cardiovascular diseases diabetes 

Role of Selenium in Health 

The impact of HIV on cancer; the role of cellular stress



Co-Supervising MPhil/PhD students working on; 

-Cytotoxic T Lymphocytes escape mutations in recently HIV infected individuals 

-Metabolites signatures in Schistosomiasis 


  1. Kasvosve I, Tshwenyego U, Phuthego T, Koto G, Zachariah M, Nyepetsi N.G and Motswaledi M.S, 2014, Serum ferritin concentration is affected by ferroportin Q248H mutation in Africans. Clinica Chimica Acts, 444, pg 257-259.
  2. Maamoun H, Zachariah M, McVey J, Green F and Abdelali Agouni, Heme Oxygenase (HO)-1 Induction Prevents Endoplasmic Reticulum Stress-Mediated Endothelial Cell Death and Impaired Angiogenic Capacity. (In review-Biochemical Pharmacology).
  3. Zachariah M, Maamoun H, Agouni A and Rayman MP, 2015. High Selenium intake is associated with endothelial dysfunction. Critical Role for Endoplasmic Reticulumn Stress. Heart. 101:A113

In pursuit of academic excellence